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diagnosis differential injury management causes aclf alcoholic autoimmune chronic cirrhosis dili druginduced failure gastroenterology hepatorenal hrs liverenzymes nephrology patterns syndrome
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... > 20x normal - Acute ... cirrhosis, Portal Vein ... #Injury #hepatology ... #LFTs #transaminitis
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... (AAH) Drug-Induced ... ) Viral Hepatitis ... Failure #Cirrhosis #Hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... , Acute biliary ... Vasculature • Hepatic Vein ... Diagnosis #Causes #Acute ... #algorithm #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... • Drugs • AIH ... • Alcoholic hepatitis ... • Others #LFTs ... #Hepatology #LiverEnzymes
Alcoholic Hepatitis - Management Algorithm 1. Severity assessed not only by MDF (>32) but also by MELD
Alcoholic Hepatitis ... - Management Algorithm ... survival in severe AH ... can be bridge to Liver ... #treatment #hepatology
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
subclinical disease to acute ... liver failure ... hepatocellular pattern of liver ... regarding need for treatment ... #Management #Hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... non-essential drug/HDS treatments ... dechallenge • Acute ... • Autoimmune hepatitis ... #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Differential Diagnosis Algorithm ... • Hepatic vein: ... differential #diagnosis #algorithm ... #hepatology
Hepatorenal Syndrome (HRS) Definition: • Functional, potentially reversible kidney impairment. • Occurs in advanced liver disease: cirrhosis, severe alcoholic
severe alcoholic hepatitis ... , or acute liver ... sympathetic + ADH ... Treatment Overview ... Hepatorenal #Syndrome #Hepatology
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