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differential injury management saag aflp albumin alcoholic coagulation dic dili disseminated druginduced fatty gradient hematology hypertension intravascular liverenzymes obgyn obstetrics
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
> 20x normal - Acute ... cirrhosis, Portal Vein ... #Injury #hepatology ... #LFTs #transaminitis ... #differential #diagnosis
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... Diagnosis Hepatocellular ... Vasculature • Hepatic Vein ... #Causes #Acute ... #algorithm #hepatology
Causes of Ascites - Differential Diagnosis Algorithm Portal Hypertension - Prehepatic: • Portal vein thrombosis • Splenic
Causes of Ascites ... Algorithm Portal ... Infiltrative disease • Acute ... liver failure ... #Algorithm #Hepatology
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
- Differential Diagnosis ... of portal HTN: ascites ... • Cirrhosis/acute ... hepatitis • Infiltrative ... #causes #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
non-essential drug/HDS treatments ... for alternative causes ... dechallenge • Acute ... disorder (e.g. ascites ... #Algorithm #hepatology
Causes of Ascites Normal Peritoneum Portal hypertension (SAAG > 1.1 g/dL) 1. Hepatic congestionl
Causes of Ascites ... - Alcoholic hepatitis ... fibrosis - Acute ... Portal vein occlusion ... #Causes #diagnosis
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... • Alcoholic hepatitis ... • Others #LFTs ... #Hepatology #LiverEnzymes ... #Algorithm #Causes
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis High albumin gradient (>1.1 g/dl): - Cirrhosis - Alcoholic
- Differential Diagnosis ... - Alcoholic hepatitis ... - Massive liver ... Veno-occlusive disease - Acute ... #hepatology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... = nonspecific (nausea ... develops (DIC, ascites ... : Viral Hepatitis ... #Pregnancy #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Algorithm Vascular ... Causes of Acute ... • Hepatic vein: ... #algorithm #hepatology
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