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diagnosis differential management acute causes transaminitis aclf alcoholic autoimmune chronic cirrhosis dili druginduced failure gastroenterology hepatocellular liverenzymes patterns
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... Injury Transaminase ... cirrhosis, Portal Vein ... #Injury #hepatology ... #LFTs #transaminitis
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Injury → liver ... • Infections: Hepatitis ... #Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Injury - Differential ... Vasculature • Hepatic Vein ... #Injury #Differential ... Causes #Acute #algorithm ... #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
months without treatment ... (AAH) Drug-Induced ... Liver Injury (DILI ... ) Viral Hepatitis ... Failure #Cirrhosis #Hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... • Drugs • AIH ... • Alcoholic hepatitis ... • Others #LFTs ... #Hepatology #LiverEnzymes
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... non-essential drug/HDS treatments ... ascites), Chronic hepatitis ... • Autoimmune hepatitis ... #Algorithm #hepatology
Alcoholic Hepatitis - Management Algorithm 1. Severity assessed not only by MDF (>32) but also by MELD
Alcoholic Hepatitis ... - Management Algorithm ... survival in severe AH ... can be bridge to Liver ... #treatment #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Differential Diagnosis Algorithm ... vein: Budd-chiari ... #injury #hepatitis ... #hepatology
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
disease to acute liver ... hepatocellular pattern of liver ... injury, though ... regarding need for treatment ... #Management #Hepatology
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