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rheumatology neurology hematology differential hemophagocytic hepatology hlh lymphohistiocytosis nephrology tb tuberculosis activetb causes dermatology erythematosus gastroenterology gravis infections latenttb lupus
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad ... Differential Diaqnoses ... • Ocular: uveitis ... #diagnosis #management ... #treatment #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... ulceration • Ocular ... (Clinical Dx). ... Arthritis, AS Treatment ... #diagnosis #management
Antiphospholipid Syndrome (APS) APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
Antiphospholipid Syndrome ... to be present Treatment ... (EULAR Guidelines ... #management #anticoagulation ... #guidelines
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... Clinical Presentation ... Treatment: • Corticosteroids ... #Syndrome #Diagnosis ... #Management #Hematology
Streptococcal Toxic Shock Syndrome (STSS) Complication of invasive GAS disease characterized by shock & MOF → occurs
Streptococcal Toxic Shock Syndrome ... of invasive GAS disease ... , erythematous macular ... #STSS #treatment ... #management #diagnosis
Oroya Fever Hematologic disease caused by Bartonella bacilliformis Restricted to the Andes highlands of Peru & Ecuador B. bacilliformis:
Fever Hematologic disease ... Clinical Presentation ... → Mular DIAGNOSIS ... TREATMENT: ​• Acute ... #management #Bartonella
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... IFN-y) → Excessive activation ... accumulation of clinical ... Assessment • Clinical ... #management #treatment
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Failure (ACLF) Clinical ... Guidelines ACLF ... months without treatment ... underlying liver disease ... #diagnosis
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... excessive macrophage activation ... age, however the disease ... #management #treatment
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia If prolonged or ≥ 39 C this is a
Hyperthermia - Guidelines ... 39 C this is a clinical ... Treatment depends ... Anesthesia #Checklist #Diagnosis ... #Management #Workup
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