9 results
Papulosquamous Skin Rash - Differential Diagnosis Algorithm
Erythrematous or violaceous papules & plaques with overlying scale
 •
Papulosquamous Skin ... especially penis) Wickham's ... soles • Discoid Lupus ... sun-exposed area #Papulosquamous
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... Mild disease- Hydroxychloroquine ... Moderate disease - Hydroxychloroquine ... #Systemic #Lupus ... #rheumatology #management
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Hydroxychloroquine ... Lupusreference #Hydroxychloroquine ... pharmacology #levels #lupus ... #management
Algorithm for the Treatment of Membranous Lupus Nephritis
Sub-nephrotic-range proteinuria (<3.5g/d, normal serum albumin) and Preserved kidney
of Membranous Lupus ... Hydroxychloroquine ... Hydroxychloroquine ... #Membranous #Lupus ... Algorithm #Treatment #management
Treatment Algorithm for Active Proliferative Lupus Nephritis (Class III/IV or Mixed Class III/IV + V)
Induction Therapy
Proliferative Lupus ... cyclophosphamide (Euro-Lupus ... monthly x 6 months Hydroxychloroquine ... Proliferative #Lupus ... #Nephritis #management
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... Drug Induced Lupus ... causal drug +++, Hydroxychloroquine ... Usual therapeutic management ... rheumatology #diagnosis #management
Hydroxychloroquine - Toxicology

 • Hydroxychloroquine (HCQ) is classified as an aminoquinoline (Antimalarial) agent.
 • It is
Hydroxychloroquine ... Toxicology • Hydroxychloroquine ... most commonly lupus ... Kat_Watson #Hydroxychloroquine ... Toxicology #diagnosis #management
Pregnancy Management in Patients with SLE and/or APS - Conception to Delivery
 • Stop Teratogenic Drugs
Pregnancy Management ... VKA) + maintain hydroxychloroquine ... #Pregnancy #Management ... #SLE #APS #lupus
Drug Induced Lupus (DIL)
 • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Drug Induced Lupus ... Epidemiology: -10% of all lupus ... causal drug +++, Hydroxychloroquine ... #DrugInduced #Lupus ... diagnosis #treatment #management