9 results
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Syndrome (MAS) ... lupus erythematosus ... (CNS) dysfunction ... [SLE], AOSD) • ... #Management #Hematology
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
may be seen in ... (PBC), or with systemic ... lupus erythematosus ... (SLE) Signs / ... #Symptoms
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... polyclinic or patchy papulosquamous ... CNS • Headache ... : • Symptoms limited ... #Systemic #Lupus
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Systemic disease ... symptoms (headache ... Oral aphthae : SLE ... #diagnosis #management ... #signs #symptoms
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
(GBS), systemic ... lupus erythematosus ... (SLE), polymyositis ... (LEMS), systemic ... myopathy #diagnosis #management
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... dysregulation: activated macrophages ... mediators such as ... skin (16-32%): lupus ... #Signs #Symptoms
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
SLE, atherosclerotic ... Symptoms (SX) in ... purpura: Strong sign ... • Progressive symptoms ... chorioretinitis, CNS
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
lupus erythematosus ... (SLE), Sjögren’ ... and the systemic ... symptoms Histopathological ... TAFRO #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
of the immune system ... (often termed MAS-HLH ... : Macrophage Activation ... Presentation • Common Signs ... and Symptoms: