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diagnosis hematology management differential leukemia vasculitis hemeonc hodgkins lupus lymphocytic lymphoma mds myelodysplastic sle algorithm apml approach arthritis criticalcare differentiation
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... microglobulin Treatment ... #Chronic #Lymphocytic ... Leukemia #diagnosis #workup ... #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, CLL Acute leukemias ... Phosphorus CLL ... ) CLL Symptoms: ... mosquito bites CLL ... #Oncology #Diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... anemia DDX: Rule Out ... Marrow Failure • Chronic ... Workup: • Complete ... #oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... = funny-shaped cells ... Allogeneic stem cell ... only curative treatment ... #hematology #oncology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
typically of B-cell ... Reed Sternberg cell ... based on: - Cell ... type (B cell, T ... #oncology #diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... Leukemia (CLL) ... Transformation to large cell ... uw_IMresidency #CLL ... #Leukemia #oncology
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
Classification of ... temporalis (giant-cell ... induced by chronic ... dermatomyositis #Size #Classification ... Vessels #Diagnosis #Rheumatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Release from blast cells ... • Induce blast cell ... #oncology
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
rheumatic fever • Chronic ... Send for cell count ... hepatitis, herpes • Chronic ... Joint #Pain #MSK #rheumatology ... #approach #workup
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... -95% of cases) Classification ... Hodgkin Lymphoma Workup ... Hodgkin Lymphoma Treatment ... #hematology #oncology
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