Frequency of ANCA Positivity in Different Conditions ANCA-Associated Vasculitis • GPA - PR3-ANCA 75%, MPO-ANCA 20%, 5% ANCA negative • MPA - PR3-ANCA 30%, MPO-ANCA 60%, 10% ANCA negative • EGPA - PR3-ANCA 5%, MPO-ANCA 45%, 50% ANCA negative • Renal-limited vasculitis - PR3-ANCA 10%, MPO-ANCA 80%, 10% ANCA negative • Drug-induced vasculitis - PR3-ANCA 10%, MPO-ANCA 90%, Often high titer, dual positivity for MPO and PR3 #ANCA #Positivity #vasculitis #sensitivity #MPO #PR3 #diagnosis #rheumatology
