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diagnosis rheumatology differential management algorithm vasculitis nephrology lupus clinical ana antinuclear causes classification erythematosus sle systemic table workup neurology testing
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Antibody) and ANCA ... 80-90%) > MPO - ANCA ... MPO: 75-80% - ANCA ... disease - MPO>PR3 - ANCA ... Antinuclear #Antibody #ANCA
ANCA Associated Vasculitis (AAV) - Auto-antibodies and Differential Diagnosis MPA → usually p-ANCA GPA → usually c-ANCA EGPA →
ANCA Associated ... MPA → usually p-ANCA ... EGPA → ANCA in ... 40-50% P-ANCA ... (MPO) C-ANCA (
ANCA-Associated Vasculitis A group of necrotizing, small-vessel vasculitis without immune complex deposition. Complement levels are normal due
ANCA-Associated ... - C-ANCA pattern ... antibody) - P-ANCA ... Hydralazine-induced ANCA ... @AnnKumfer #ANCA
Pathogenesis of ANCA-associated vasculitis Dr. Muner Mohamed @MunerMohamed1 #ANCA #vasculitis #pathophysiology #nephrology
Pathogenesis of ANCA-associated ... MunerMohamed1 #ANCA
Approach to managing Glomerulonephritis (GN) in children. ANCA, antineutrophil cytoplasmic antibodies; c-ANCA, cytoplasmic antineutrophil cytoplasmic antibodies;
ANCA, antineutrophil ... antibodies; c-ANCA ... hypertension; p-ANCA
Glomerulonephritis - Differential Diagnosis Framework ANCA: • C-ANCA: GPA (Wegener's) • P-ANCA: Microscopic Polyangiitis, Eosinophilic GPA (Churg
Diagnosis Framework ANCA ... : • C-ANCA: GPA ... Wegener's) • P-ANCA
ANCA Vasculitis - GPA, MPA, Eosinophilic GPA doi:10.1038/s41572-020-0204-y #ANCA #Vasculitis #GPA #MPA #Eosinophilic #rheumatology #diagnosis #comparison #table
ANCA Vasculitis ... s41572-020-0204-y #ANCA
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Negative IF): • PR3-ANCA ... (C-ANCA): GPA > ... > eGPA • MPO-ANCA ... (P-ANCA): eGPA,
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
VESSEL VASCULITIS: ANCA ... Associated - ANCA ... proteinase 3 (PR3-ANCA ... Granulomas - ANCA ... Granulomas - ANCA
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
• Lupus (SLE): ANA ... Polymerase Ill • ANCA ... Vasculitis: P-ANCA ... perinuclear), C-ANCA
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