Balanced Crystalloids vs. NormalSaline - My infographic about SALT-ED and SMART trial comparing crystalloids and saline for the critically and noncritically ill patients.
SALT-ED - Balanced Crystalloids versus Saline in Noncritically Ill Adults
- No difference in hospital-free days between treatment with BC and NS.
- Stage 2 AKI patients or those with borderline renal failure or hyperchloremia had the largest benefit from balanced crystalloids.
March 1, 2018 N Engl J Med 2018; 378:819-828 https://www.nejm.org/doi/full/10.10
SMART - Balanced Crystalloids versus Saline in Critically Ill Adults
- The use of balanced crystalloids resulted in a lower rate of MAKE30 than the use of saline.
- The largest benefit appears to be in the septic subset of patients with a NNT of 20.
March 1, 2018 N Engl J Med 2018; 378:829-839 https://www.nejm.org/doi/10.1056/NE
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