Cardiac Auscultation Practice - Aortic Stenosis Aortic Stenosis: trace a circle over the back of your hand – you get the crescendo-decrescendo sound – cool! Setup: https://twitter.com/ptfaddenMD/status/1268523183004626944 By Dr. Patrick Fadden @ptfaddenMD #Aortic #Stenosis #HeartSounds #Cardiac #Auscultation #Practice #PhysicalExam #Clinical #Video #Stethoscope #Hand

Cerebral Toxoplasmosis - Most comrnon CNS infection in patients with AIDS who are not receiving appropriate prophylaxis Clinical • Headache • Fever • Altered mental status • Seizure Management First line • Sulfadiazine and pyrimethamine • Leucovorin (co-administer to prevent pyrimethamine-induced hematologic toxicity) Second line • Clindamycin plus pyrimethamine plus leucovorin • Atovaquone plus pyrimethamine plus leucovorin #Cerebral #Toxoplasmosis #Diagnosis #Overview #Management

Maculopapular Rashes - THE ALGORITHMIC APPROACH The term maculopapule is a portmanteau, a combination of macule and papule (Table 1, page 8). Maculopapular rashes are differentiated based on the distribution of the rash and systemic toxicity (Figure 3, page 10). Patients with centrally distributed rashes who appear toxic and febrile have a wide differential diagnosis; however, it is paramount that patients living in endemic areas be assessed for Lyme disease. Those with centrally distributed rashes but without signs of toxicity usually present with either a drug reaction or pityriasis rosea. Patients with peripherally distributed rashes have a broader differential diagnosis, which is dependent upon systemic toxicity, presence or absence of target lesions, and whether the rash is located on the flexor or extensor surfaces. Target lesions are pathognomonic for SJS or EM. Patients with peripheral lesions and systemic toxicity but without target lesions require emergent evaluation for meningococcemia, RMSF, and syphilis. Nontoxic patients with a peripherally distributed rash but without target lesions require further assessment for flexor involvement (scabies or eczema) or extensor involvement (psoriasis). #Diagnosis #Dermatology #Maculopapular #Rash #Algorithm #Central #Peripheral #Differential

Infection-Related Cancers Viruses: • HPV - Cervical, anogenital, head and neck, skin cancer • HTLV-1 - Adult T-cell Leukemia • HIV - NHL, Kaposi's sarcoma, Merkel cell carcinoma • HBV / HCV - Hepatocellular carcinoma • HHV-8 - Kaposi's sarcoma • EBV - NHL, Hodgkin's lymphoma, Burkitt's lymphoma, nasopharyngeal, gastric cancer • Merkel cell polyomavirus - Merkel cell carcinoma • BK Polyomavirus - Bladder cancer Bacteria: • Helicobacter pylori - MALToma, Gastric cancer • Streptococcus bovis - Colorectal cancer Parasites: • Clonorchis sinensis - Cholangiocarcinoma • Opisthorchis viverrini - Cholangiocarcinoma • Schistosoma haematobium - Bladder cancer • Schistosoma japonicum - Colorectal cancer by Dr. Keith Siau @drkeithsiau #Infection #Associations #Cancers #oncology #differential #diagnosis #table

Findings in Cerebrospinal Fluid in Different Causes of Meningitis #CSF #Fluid #Analysis #Interpretation #Meningitis #Normal #Bacterial #Viral #Comparison #Table #Diagnosis #Infection