Dr. Gerald Diaz @GeraldMD
32.7M 13.9K 7.4K
Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief πŸ‡΅πŸ‡­ πŸ‡ΊπŸ‡Έ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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NOAC / DOAC Pharmacology and Prescribing Cheat Sheet
Novel (or Direct) Oral Anti-Coagulants
 β€’ Rivaroxaban
 β€’ Apixaban
NOAC / DOAC Pharmacology ... #NOAC #DOAC #Pharmacology ... #Prescribing #hematology
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
#Medications #Pharmacology ... Pathophysiology #Mechanisms #DOAC ... #Hematology
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
DOAC: Cheat Sheet ... @Bloodman #DOAC ... Anticoagulation #Hematology ... #Pharmacology # ... Dabigatran #Edoxaban #NOAC
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Clotmaster #VTE #DOAC ... #Loading #DVT #Pharmacology ... #Hematology
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
stratification algorithm ... anticoagulants (DOACs ... filtration rate; DOAC ... #Cancer #Algorithm ... Anticoagulation #Management #Hematology
β–Ί
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
(DOAC interactions ... DOACs are substrates ... metabolization of DOACs ... Chemotherapy #Oncology #Hematology ... Interactions #Table #Pharmacology
Glucose-lowering medication in type 2 diabetes - Algorithm

#Diabetes #Medications #Algorithm #Pharmacology #Pharmacotherapy #Hypoglycemic #Management #Endocrinology
type 2 diabetes - Algorithm ... #Medications #Algorithm ... #Pharmacology # ... Hypoglycemic #Management #Endocrinology
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 β€’ Apixaban,
DOAC Reversal Emergency ... not available #DOAC ... #Reversal #NOAC ... anticoagulant #hematology ... #management #pharmacology
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
Treatment algorithm ... Suggested treatment algorithm ... DOAC, direct oral ... #DOAC #VTE #Malignancy ... Anticoagulation #Management #Hematology
Anticoagulant Bridging

 β€’ Switching from LMWH
 β€’ Switching from UFH
 β€’ Switching from DOAC to Warfarin
Switching from DOAC ... from Warfarin to DOAC ... anticoagulation #pharmacology ... #management #hematology