Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief πŸ‡΅πŸ‡­ πŸ‡ΊπŸ‡Έ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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22 results
Summary of Coagulation Deficiencies
Inherited:
 β€’ Hemophilia A - Deficiency of Factor VIII
 β€’ Hemophilia B -
Malabsorption (e.g ... warfarin, DOACs (e.g ... ) β€’ Advanced Liver ... disorders (e.g. ... comparison #diagnosis #hematology
Clinical Diagnosis of Autoimmune Hepatitis
 - Onset of jaundice within prior 8 weeks
 - Ongoing consumption
of Autoimmune Hepatitis ... (e.g., severe upper ... use assessment (e.g ... laboratory tests (e.g ... #Hepatology #AIH
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 β€’ Infectious: Hepatitis C, A,
Injury - Differential ... Other: NAFLD, Autoimmune ... hepatitis, Acute ... #Injury #Differential ... Acute #algorithm #hepatology
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Dermatomyositis Anti-LKM (liver ... - Vasculitis, e.g ... - Vasculitis, e.g ... diseases #diagnosis #table ... #rheumatology #
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
Autoimmune Hepatitis ... inflammation (eg ... been reported (eg ... Histology Findings (eg ... Diagnosis #Management #Hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury β†’ liver test abnormalities without evidence of liver
Injury - Differential ... β€’ Infections: Hepatitis ... Other: NAFLD, Autoimmune ... #Diagnosis #hepatology ... Transaminitis #LFTs #hepatitis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 β€’ Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... (usually IgM) (e.g ... deficiencies (e.g ... Extravascular #Causes #differential ... #diagnosis #hematology
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 β€’ Acute infection
 β€’ Solid organ
Thrombocytosis - Differential ... inflammatory disorders (e.g ... . autoimmune, TB ... Thrombocytosis #Differential ... Diagnosis #Causes #hematology
Acquired von Willebrand Syndrome - Diagnosis and Management
 β€’ Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Lymphoproliferative disorders (e.g ... Myeloproliferative disorders (e.g ... thrombocythemia), Autoimmune ... Management #treatment #hematology ... #differential
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
hemolytic anemia (e.g ... Microspherocytes: Autoimmune ... Smear #Analysis #hematology ... interpretation #clinical