Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief 🇵🇭 🇺🇸 - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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toxicity management differential agitation ammonia aspirin causes clozapine colchicine criticalcare delirium drug gitelman hyperammonemia icu infusion lacticacidosis mala medications metformin
Metformin Associated Lactic Acidosis (MALA) Pathophysiology of MALA - Metformin interferes with the activity of the
Acidosis (MALA) Pathophysiology ... use in cellular metabolism ... Diagnosis of MALA ... LacticAcidosis #Toxicity #Toxicology ... #Diagnosis #Management
Serotonin Syndrome Drug Precipitants and Pharmacology ↑ Serotonin Formation: Tryptophan, Oxitriptan ↑ Serotonin Release: Amphetamines, Cocaine, Mirtazapine ↑ Serotonin
Serotonin Syndrome ... Precipitants and Pharmacology ... Lithium ↓ Serotonin Metabolism ... #Pharmacology # ... #differential #diagnosis
Gitelman Syndrome Pathophysiology Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Pathophysiology ... → Hypokalemia Metabolic ... #Pathophysiology ... #nephrology #diagnosis
Clozapine Toxicology Clozapine is an atypical antipsychotic most often reserved for use in patients who have treatment-resistant
Clozapine Toxicology ... - Metabolism - ... #Clozapine #Toxicology ... #Toxicity #Diagnosis ... #Pharmacology
Propofol-Related Infusion Syndrome (PRIS) Diagnosis is based on a constellation of clinical suspicion and biochemical signs including:
(PRIS) Diagnosis ... Hyperlactatemia • Metabolic ... #PRIS #Diagnosis ... #Management #Pharmacology ... #Toxicity #Toxicology
Tramadol - Toxicology Due to different CYP-2D6 genotypes, people variably metabolize tramadol into its active metabolite, M1 This
Tramadol - Toxicology ... people variably metabolize ... #Tramadol #Toxicology ... #Toxicity #Diagnosis ... #Pharmacology
Schematic representation of the major sources of ammonia production and its excretory pathway (GI = gastrointestinal,
and decreased metabolism ... rare): - Reye syndrome ... deficiency #Ammonia #Pathophysiology ... #Differential #Diagnosis
Phases of Colchicine Toxicity - Early Phase (0-24h) - Multi-organ failure Phase (1-7 days)
Respiratory Distress Syndrome ... : Metabolic acidosis ... Colchicine #Toxicity #Toxicology ... #Phases #Pharmacology ... #Diagnosis
Pain, Agitation, and Delirium (PAD) in the ICU Addressing the ICU Triad (PAD) can be accomplished through
Propofol infusion syndrome ... Versed) - CYP3A4 metabolism ... No pharmacologic ... (Haldol) - No pharmacologic ... #CriticalCare #diagnosis
Salicylate Poisoning - Toxicology Acute toxicity = vomiting, tachypnea, tinnitus, diaphoresis, and lethargy. This may progress to
Salicylate Poisoning - Toxicology ... alkalosis and metabolic ... Salicylate #Toxicity #Toxicology ... #Pharmacology # ... Diagnosis #Management
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