Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief πŸ‡΅πŸ‡­ πŸ‡ΊπŸ‡Έ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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11 results
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Acidosis (MALA) Pathophysiology ... Diagnosis of MALA ... presentation - Clinical ... LacticAcidosis #Toxicity #Toxicology ... #Diagnosis #Management
Serotonin Syndrome Drug Precipitants and Pharmacology
↑ Serotonin Formation: Tryptophan, Oxitriptan
↑ Serotonin Release: Amphetamines, Cocaine, Mirtazapine
↑ Serotonin
Serotonin Syndrome ... Lithium ↓ Serotonin Metabolism ... #Pharmacology # ... medications #causes #differential ... #diagnosis #drug
Purple Urine Bag Syndrome
Chronic, indwelling catheter + bacteriuria (Providencia, Klebsiella, E.coli*) + alkaline urine
Tryptophan β†’ Indoxyl
Purple Urine Bag Syndrome ... #PUBS #pathophysiology ... #clinical #photo ... #differential # ... diagnosis
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 β€’ Defect in fetal free fatty acid metabolism products β†’
Pregnancy (AFLP) Pathophysiology ... free fatty acid metabolism ... Intermediate fatty acid metabolism ... infiltration) Differential ... Diagnosis: Viral
Imaging Patterns of Toxic and Metabolic Brain Disorders

Thalami, Mammillary Bodies and Tectum: Wernicke Encephalopathy
Dentate Nuclei: Metronidazole,
Patterns of Toxic and Metabolic ... MRI #Patterns #Toxicology ... #Disorders #Clinical ... #Differential # ... Diagnosis #Radiology
Propofol-Related Infusion Syndrome (PRIS)

Diagnosis is based on a constellation of clinical suspicion and biochemical signs including:
(PRIS) Diagnosis ... constellation of clinical ... Hyperlactatemia β€’ Metabolic ... #Management #Pharmacology ... #Toxicity #Toxicology
Causes of Neuromuscular Weakness
 β€’ Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Guillain-Barre syndrome ... heavy metals), Critical ... Malnutrition, Metabolic ... Weakness #Causes #differential ... #diagnosis #neurology
Schematic representation of the major sources of ammonia production and its excretory pathway (GI = gastrointestinal,
and decreased metabolism ... rare): - Reye syndrome ... deficiency #Ammonia #Pathophysiology ... Hyperammonemia #Differential ... #Diagnosis
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or β‰₯ 39 C this is a
39 C this is a clinical ... dissipation of metabolic ... β€’ Serotonin syndrome ... #Hyperthermia #Differential ... Anesthesia #Checklist #Diagnosis
Phases of Colchicine Toxicity
 - Early Phase (0-24h) 
 - Multi-organ failure Phase (1-7 days)
Respiratory Distress Syndrome ... : Metabolic acidosis ... Colchicine #Toxicity #Toxicology ... #Phases #Pharmacology ... #Diagnosis