Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief πŸ‡΅πŸ‡­ πŸ‡ΊπŸ‡Έ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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Salicylate Toxicity - Diagnosis and Management

Clinical Findings
Pathophysiology
Workup
Treatment

By Stacy Marshall, MD

#Salicylate #Toxicity #Diagnosis #Management #Toxicology #Aspirin #Treatment
Salicylate Toxicity ... Clinical Findings Pathophysiology ... Workup Treatment ... #Toxicology #Aspirin ... #Treatment
Cyanide Toxicity 
Treatment:
1) Hydroxocobalamin + Cyanide = Cyanocobalamin (nontoxic) 
   or 
2) Amyl nitrite
Cyanide Toxicity ... Treatment: 1 ... #Cyanide #Toxicity ... #Toxicology #Pathophysiology ... #Management #Treatment
LOW MOLECULAR WEIGHT HEPARIN (LMWH) DOSING RECOMMENDATIONS (Enoxaparin and Dalteparin):
 - VTE PROPHYLAXIS
 - VTE TREATMENT
HEPARIN (LMWH) DOSING ... PROPHYLAXIS - VTE TREATMENT ... ACUTE CORONARY SYNDROME ... #Prophylaxis #Pharmacology ... #Management
Intravenous Lipid Emulsion (ILE) Therapy

ILE is a treatment for severe toxicity from local anesthetics. In addition,
Therapy ILE is a treatment ... for severe toxicity ... life-threatening toxicity ... #ILE #Therapy #Toxicology ... #Management #Pharmacology
Salicylate Toxicity - Diagnosis and Management

Consider if:
1) Patient is hot and altered
2) You see tachypnea with
Salicylate Toxicity ... Diagnosis and Management ... #Salicylate #Aspirin ... #Toxicity #Toxicology ... #Treatment
Management of Serotonin Syndrome
Identify and stop all serotoninergic medications
 β€’ Avoid inadvertent Rx of serotoninergic meds
Management of Serotonin ... Syndrome Identify ... β€’ Dosing: 12mg loading ... #Management #treatment ... #toxicology
Salicylate Poisoning - Toxicology

Acute toxicity = vomiting, tachypnea, tinnitus, diaphoresis, and lethargy. This may progress to
Salicylate Poisoning - Toxicology ... Acute toxicity ... #Toxicology #Pharmacology ... #Diagnosis #Management ... #Aspirin
Propofol-Related Infusion Syndrome (PRIS)

Diagnosis is based on a constellation of clinical suspicion and biochemical signs including:
Propofol-Related Infusion Syndrome ... Related #Infusion #Syndrome ... PRIS #Diagnosis #Management ... #Pharmacology # ... Toxicity #Toxicology
Methotrexate Toxicology 

Intravenous leucovorin (folinic acid) treatment serves as a cofactor necessary for synthesis of thymidylate
Methotrexate Toxicology ... (folinic acid) treatment ... Leucovorin dosing ... #Toxicity #Management ... #Pharmacology
Management of Anthracyclines and HER2 Antagonist Cardiotoxicity
Anthracyclines cause cardiomyopathy:
 βœ– Reduction in left ventricular ejection fraction
Management of Anthracyclines ... ) and initiate treatment ... every 3 months during ... cardiology #oncology #pharmacology ... #toxicity #chemotherapy