Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief πŸ‡΅πŸ‡­ πŸ‡ΊπŸ‡Έ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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Clozapine Toxicology
Clozapine is an atypical antipsychotic most often reserved for use in patients who have treatment-resistant
Clozapine Toxicology ... Clozapine is an ... patients who have treatment-resistant ... #Toxicology #Toxicity ... #Diagnosis #Pharmacology
Cyanide Toxicity 
Treatment:
1) Hydroxocobalamin + Cyanide = Cyanocobalamin (nontoxic) 
   or 
2) Amyl nitrite
Cyanide Toxicity ... Treatment: 1 ... #Cyanide #Toxicity ... #Toxicology #Pathophysiology ... #Management #Treatment
Therapeutic Drug Level Monitoring 
Carbamazepine - Sample immediately before next dose (trough) 
Clozapine - Sample immediately
dose (trough) Clozapine ... at anytime if toxicity ... - Intermittent dosing ... Therapeutic #Ranges #Toxicology ... #Pharmacology #
LOW MOLECULAR WEIGHT HEPARIN (LMWH) DOSING RECOMMENDATIONS (Enoxaparin and Dalteparin):
 - VTE PROPHYLAXIS
 - VTE TREATMENT
HEPARIN (LMWH) DOSING ... PROPHYLAXIS - VTE TREATMENT ... ACUTE CORONARY SYNDROME ... THERAPY #LMWH #Dosing ... #Prophylaxis #Pharmacology
Intravenous Lipid Emulsion (ILE) Therapy

ILE is a treatment for severe toxicity from local anesthetics. In addition,
Therapy ILE is a treatment ... for severe toxicity ... life-threatening toxicity ... #ILE #Therapy #Toxicology ... #Management #Pharmacology
Summary of Recommendations for the Treatment of Aspergillosis - IDSA Guidelines
 - Invasive syndromes of Aspergillus
Recommendations for the Treatment ... or colonizing syndromes ... Aspergillosis #Treatment ... #pharmacology # ... dosing #medications
Salicylate Toxicity - Diagnosis and Management

Clinical Findings
Pathophysiology
Workup
Treatment

By Stacy Marshall, MD

#Salicylate #Toxicity #Diagnosis #Management #Toxicology #Aspirin #Treatment
Salicylate Toxicity ... Clinical Findings Pathophysiology ... Workup Treatment ... Diagnosis #Management #Toxicology ... #Aspirin #Treatment
Management of Serotonin Syndrome
Identify and stop all serotoninergic medications
 β€’ Avoid inadvertent Rx of serotoninergic meds
Management of Serotonin Syndrome ... β€’ Dosing: 12mg loading ... ucsdim #Serotonin #Syndrome ... #Management #treatment ... #toxicology
Drug-Induced Prolonged QTc

QTc >500ms is an independent risk factor for developing Torsades des Pointes (TdP)
Drugs causing
Chlorpromazine, Clozapine ... Prolonged #QTc #Toxicity ... #Toxicology #Pharmacology
Propofol-Related Infusion Syndrome (PRIS)

Diagnosis is based on a constellation of clinical suspicion and biochemical signs including:
Propofol-Related Infusion Syndrome ... Related #Infusion #Syndrome ... Diagnosis #Management #Pharmacology ... #Toxicity #Toxicology