Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief πŸ‡΅πŸ‡­ πŸ‡ΊπŸ‡Έ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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6 results
Intravenous Lipid Emulsion (ILE) Therapy

ILE is a treatment for severe toxicity from local anesthetics. In addition,
treatment for severe toxicity ... life-threatening toxicity ... #Therapy #Toxicology ... #Management #Pharmacology ... #Overdose #intralipid
Propofol-Related Infusion Syndrome (PRIS)

Diagnosis is based on a constellation of clinical suspicion and biochemical signs including:
Propofol-Related Infusion ... Syndrome (PRIS) ... #Diagnosis #Management ... #Pharmacology # ... Toxicity #Toxicology
Naloxone - Toxicology

Adult starting dose:
 - 0.4 mg IV/IM/IO/SQ for non-opioid dependent patients
 - 0.04 mg
Naloxone - Toxicology ... If an infusion is ... Naloxone #Narcan #Toxicology ... #Management #Pharmacology ... #Overdose
Anti-IL6 Agents (Tocilizumab, Siltuximab) in COVID19

IL-6 activates T cells and macrophages, among other cell types (see
Anti-IL6 Agents ... Cytokine Activation Syndrome ... ALT) > 22% - Infusion ... Siltuximab #COVID19 #Pharmacology ... #Management #Medications
Pain, Agitation, and Delirium (PAD) in the ICU
Addressing the ICU Triad (PAD) can be accomplished through
Propofol infusion ... syndrome (PRIS) ... glycol (solvent) toxicity ... No pharmacologic ... CriticalCare #diagnosis #management
Methotrexate Toxicology 

Intravenous leucovorin (folinic acid) treatment serves as a cofactor necessary for synthesis of thymidylate
Methotrexate Toxicology ... the most severe overdoses ... evidence of marrow toxicity ... #Toxicity #Management ... #Pharmacology