Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief πŸ‡΅πŸ‡­ πŸ‡ΊπŸ‡Έ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
Syndrome Step ... /nephritic syndromes ... hematuria (RBC casts ... #Algorithm #Nephrology ... #Diagnosis
Differentiation Between Nephrotic Syndrome and Nephritic Syndrome 
== Nephrotic Syndrome ==
Onset - Insidious 
Edema - ++++
Blood
Syndrome and Nephritic ... Red blood cell casts ... Red blood cell casts ... #Comparison #Table ... #Nephrology #Diagnosis
Urinary Casts and Disease Associations
Hyaline - May be nonspecific; seen in normal individuals or during severe
Urinary Casts and ... breakdown of cellular casts ... heme-granular casts ... 34t5DgJ #Urinary #Casts ... #Diagnosis #Nephrology
Urine Microscopy - Casts
Acellular Casts
 β€’ Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... suggestive of nephrotic ... sydnrome β€’ Pigment ... #Urine #Microscopy ... #diagnosis
Atlas of Urine Microscopy Findings
 β€’ Epithelial cells - Normal
 β€’ Renal tubular cells - Acute
β€’ Red cell casts ... β€’ White cell casts ... disease β€’ Granular casts ... disorders or excreted medications ... #nephrology #casts
Simplified Approach to Acute Kidney Injury (AKI)
1) IS THIS AN EMERGENCY? 
Is there a dialysis indication
Urinary obstruction, Nephrotoxic ... PROBLEM ~80% of AKI cases ... Assess UA w/ microscopy ... for WBCs, RBCs, casts ... #diagnosis #nephrology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Kidney Injury - AKI Workup ... and Differential Diagnosis ... dipstick, urine microscopy ... β€’ Interstitial nephritis ... #nephrology #causes
Summary of characteristic abnormalities of selected glomerular diseases
Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
EM) Haematuria/nephritis ... Haemolytic-uraemic syndrome ... Nephrotic syndrome ... pathology #comparison #table ... #diagnosis #microscopy
Staphylococcus-associated GlomeruloNephritis - Diagnosis and Management Summary
CLINICAL
 β€’ Nephritic syndrome (Casts)
 β€’ Marked proteinuria (may be
GlomeruloNephritis - Diagnosis ... CLINICAL β€’ Nephritic ... syndrome (Casts ... proteinuria (may be nephrotic ... GlomeruloNephritis #nephrology
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
Renal Loses - Medications ... #Differential #Diagnosis ... Low #Magnesium #Table ... Classification #Causes ... #Workup #hypomg