Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief πŸ‡΅πŸ‡­ πŸ‡ΊπŸ‡Έ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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Signs and Symptoms of Toxidromes

Sympathomimetic / GABAergic withdrawal 
Cholinergic 
Anticholinergic 
Opioid withdrawal 
Neuroleptic malignant syndrome 
Serotonin
Anticholinergic Opioid ... #Toxidromes #Comparison ... #Table #Anticholinergics ... #Opioids #Sympathomimetics ... #Diagnosis #Toxicology
Common sodium channel blockers which cause QRS widening.

Anticonvulsants: 
 - Carbamazepine 
Antidysrhythmics:  
 - Group
- Cocaine Opioids ... QRS #widening #ECG ... #EKG #Pharmacology ... #Medications #Toxicology ... #Diagnosis #Differential
A toxidrome is a syndrome (set of symptoms) caused by specific medications or toxins.

There are 5
phyostigmine) - Opioid ... barbituates, β€œZ-drugs ... antihistamines #Diagnosis ... #Toxicology #Toxidromes ... #Comparison #Table
Toxidromes Summary Table
Heart Rate - Respiratory Rate - Blood Pressure - Mental Status - Skin -
Toxidromes Summary Table ... - Reflexes β€’ Opioid ... #Toxidromes #comparison ... #table #toxicology ... #diagnosis
Potassium Channel Blockers - Medications
1. Cardiovascular Drugs
2. Psychiatric drugs
3. Other drugs
4. Synthetic opioids: Levomethadyl 
5. Opium
Other drugs 4. ... Synthetic opioids ... #Differential #Diagnosis ... #Pharmacology # ... Toxicology
Toxidromes Compared: Anticholinergic, Cholinergic, Opioid, Sympathomimetic, Sedative-Hypnotic

During your physical exam, look for evidence of some of
, Cholinergic, Opioid ... Opioid toxicity ... #Diagnosis #Toxicology ... #Toxidromes #Comparison ... #Table #Anticholinergics
Shock and Vasoactive Drugs 
1) Determine type and etiology of shock
 β€’ Distributive: Sepsis, Anaphylaxis, Neurogenic
pharmacology ... #pharmacology # ... inopressors #diagnosis ... #management #comparison ... #table
Drug-Induced Prolonged QTc

QTc >500ms is an independent risk factor for developing Torsades des Pointes (TdP)
Drugs causing
Drug-Induced Prolonged ... Prochlorperazine β€’ Opioids ... QTc #Toxicity #Toxicology ... #Pharmacology # ... Diagnosis #prolongation
Pancreatitis management checklist 
Evaluation to guide etiology & management 
 - RUQ ultrasound 
 - Calcium
potentially causative drugs ... septic shock (e.g ... - Opioids may ... limit them as able ... Pancreatitis #Checklist #Diagnosis
Therapeutic Drug Level Monitoring 
Carbamazepine - Sample immediately before next dose (trough) 
Clozapine - Sample immediately
Therapeutic Drug ... Therapeutic #Ranges #Toxicology ... #Pharmacology # ... Diagnosis #Table