Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief πŸ‡΅πŸ‡­ πŸ‡ΊπŸ‡Έ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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Differential diagnosis of Langerhans cell histiocytosis.
Nodular LCH:
- Sarcoidosis: perilymphatic distribution.
- Metastases: random distribution.
Cystic LCH:
- LAM: round
Cystic LCH: - LAM ... Centrilobular emphysema ... #Cysts #Differential ... #Comparison #Table ... #RadiologyAssistant
Low Attenuation pattern 
1. Lymphangiomyomatosis (LAM): uniform cysts in woman of child-bearing age; no history of
LCH: multiple round ... Centrilobular emphysema ... #Clinical #Radiology ... #HRCT #CTChest ... #RadiologyAssistant
Low Attenuation pattern (2) 
1. Centrilobular emphysema: low attenuation areas without walls. Notice the centrilobular artery
Centrilobular emphysema ... histiocytosis (LCH ... #Clinical #Radiology ... #HRCT #CTChest ... #RadiologyAssistant
The fourth pattern includes abnormalities that result in decreased lung attenuation or air-filled lesions.
These include:
- Emphysema
-
- Lung cysts (LAM ... on the basis of HRCT ... #Diagnosis #Radiology ... LowAttenuation #Differential ... #RadiologyAssistant
Upper lung zone preference is seen in:
- Inhaled particles: pneumoconiosis (silica or coal)
- Smoking related diseases
(centrilobular emphysema ... edema #Diagnosis #Radiology ... #Pulmonary #HRCT ... #ChestCT #Differential ... #Table #Distribution
Differential diagnosis on HRCT
Most of our knowledge about imaging findings in interstitial lung disease comes from
Differential diagnosis ... low attenuation (table ... The cystic pattern ... #Diagnosis #Radiology ... #RadiologyAssistant
Central distribution is seen in sarcoidosis and cardiogenic pulmonary edema.
Peripheral distribution is mainly seen in cryptogenic
#Diagnosis #Radiology ... #Pulmonary #HRCT ... #ChestCT #Differential ... #Table #Distribution ... Central #Peripheral #RadiologyAssistant
Nodular pattern(2)
1. Sarcoidosis: nodules with perilymphatic distribution, along fissures, adenopathy.
2. TB: Tree-in-bud appearance in a patient
before the typical cysts ... #Clinical #Radiology ... #HRCT #CTChest ... Pattern #Comparison #Table ... #RadiologyAssistant
Cystic versus Reticular
It can be difficult to determine whether we are dealing with a reticular pattern
histiocytosis (LCH ... LCH is called a ... of such cases a HRCT ... #Clinical #Radiology ... #RadiologyAssistant
Emphysema, when it is severe, can mimick Langerhans cell histiosytosis.
When it extends beyond the centrilobular area
look as if it is cystic ... patients with LCH ... pathologist may find LCH ... #Clinical #Radiology ... #RadiologyAssistant