Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief πŸ‡΅πŸ‡­ πŸ‡ΊπŸ‡Έ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... age, however the disease ... rapidly, and empiric antibiotic ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)β†’Activation of CD8 T cells (IFN-y) β†’ Excessive activation of macrophages
β€’ Autoimmune diseases ... Unknown cause Treatment ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary ... #rheumatology
Behcet's Syndrome - Treatment
Ulcers:
 β€’ Treatment: Topical steroids
 β€’ Prevention: Colchicine
 β€’ Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome ... Topical steroids β€’ Prevention ... #Syndrome #Treatment ... #management #pharmacology ... #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Treatment
Primary HLH:
 - HLH-94 Protocol
    β€’ Dexamethasone
associated with infection ... or autoimmune disease ... for refractory disease ... #Treatment #management ... #hematology
Clarkson’s Disease - Capillary leak syndrome
Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
Capillary leak syndrome ... flares: β€’ Prevention ... of infections) ... #diagnosis #management ... #rheumatology
Complications after Bariatric Surgery
Post Bariatric Intestinal Failure:
 β€’ Severe protein malnutrition after bariatric surgery
 β€’ More
Consider refeeding syndrome ... nutrients β€’ TPN for treatment ... complication rate (i.e. infections ... Liver Disease in ... and prevention
Clotmaster Consensus 2019: Duration of Therapy for Venous Thromboembolic Disease
 β€’ Superficial Venous Thrombosis
 β€’ Upper
Thromboembolic Disease ... DVT or PE - Prevention ... post-thrombotic syndrome ... #DVT #hematology ... #length #treatment
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 β†’ start cefepime Β± vancomycin (if
if SSTI or port infection ... abdominal pain; full infectious ... 500 β†’ may stop antibiotics ... ): - Hematologic ... weakness, urinary retention
IDSA Recommendations for Preventing and Treating Histoplasma Capsulatum Infections in HIV-AIDS
Indications for Initiating Primary Prophylaxis:
 β€’
Recommendations for Preventing ... Histoplasma Capsulatum Infections ... Severe Disseminated Disease ... with ARV (see Table ... #Treatment #management
IDSA Recommendations for Preventing and Treating Disseminated Mycobacterium Avium Complex in HIV-AIDS
Preventing 1st Episode of Disseminated
Recommendations for Preventing ... Disseminated MAC Disease ... please refer to Table ... #Treatment #management ... opportunistic #infections