The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Retinopathy of Prematurity: Pathogenesis and clinical findings
Increased metabolic demand of growing eye
-> Excessive VEGF production ->
-> Neovascular complications ... Prematurity #peds #pediatrics ... pathophysiology #ophthalmology
Falls: Pathogenesis and Complications
Poly-pharmacy
Disorders affecting movement and balance
 - Sensory deficits
 - Neuromuscular degeneration/Cerebrovascular disease
 -
Pathogenesis and Complications ... Lifestyle #Geriatrics ... pathophysiology #complications
Acquired Immunodeficiency Syndrome (AIDS): Summary of Causes and Ocular Manifestations
 • Molluscum lesions
 • Eyelid Kaposi
#AIDS #Ocular #Complications ... #ophthalmology
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Signs/Symptoms/Complications ... pathophysiology #peds #pediatrics
Spondylosis - Pathogenesis and Complications

Vertebral disease that may compress the vertebral canal from all sides
Note: Do
Pathogenesis and Complications ... pathophysiology #msk #complications
Fecal Incontinence - Pathogenesis and Complications
Continence mechanisms are impaired
 • Local neuronal damage
 • External and
Pathogenesis and Complications ... #Incontinence #geriatrics
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Signs / Symptoms / Complications ... pathophysiology #ophthalmology
Complications of Measles: Pathogenesis and Clinical Findings
 • ADEM -> Fever, headache, neck stiffness, BBD, mental
Complications of ... infections #Measles #Complications
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Signs / Symptoms / Complications ... pathophysiology #geriatrics
Diabetic Retinopathy: Pathogenesis and clinical findings

Mild Non-proliferative DR
 • Outpouchings of the weakened capillary walls or
Retinopathy #Diabetes #ophthalmology ... #diagnosis #complications