The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Keratoconus: Pathogenesis and Clinical Findings
Genetics
 • Family history of keratoconus
 • Ehlers-Danlos syndrome
 • Down, Turner,
Ehlers-Danlos syndrome ... Decr Protease inhibitors ... Biomechanical Factors • Contact ... rubbing • Atopic diseases ... / Symptoms / Complications
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Alzheimer’s Disease ... mutations - Down syndrome ... chromosome 21) Signs ... / Symptoms / Complications ... pathophysiology #geriatrics #diagnosis
Kawasaki Disease: Clinical Findings
Diagnostic Criteria - Fever and 4/5 of the following:
 • Conjunctivitis
 • Polymorphous
Kawasaki Disease ... Clinical Findings Diagnostic ... Criteria - Fever ... /Symptoms/Complications ... #Criteria #Diagnosis
Conduct Disorder (CD): Pathogenesis and clinical findings
 - Must have >3 symptoms present in the past
Conduct Disorder ... >18 years old, criteria ... #CD #BehavioralDisorder ... Pathophysiology #diagnosis ... #symptoms #signs
Oppositional Defiant Disorder (ODD): Pathogenesis and clinical findings
 - Must have >4 symptoms for >6 months,
to progress to conduct ... OppositionalDefiant #ODD #BehavioralDisorder ... Pathophysiology #diagnosis ... #symptoms #signs ... #psychiatry #criteria