The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Post-Traumatic Stress Disorder (PTSD)
Neurochemical abnormalities
 • Hyper-vigilance
 • Emotional hyper-arousal
 • Exaggerated startle reflex
 • Anxiety
startle reflex • Anxiety ... of trauma • Avoidance ... StressDisorder #PTSD #BehavioralDisorder
Obsessive-Compulsive Disorder (OCD): Pathogenesis and clinical findings

Psychological Hypothesis
 • Cognitive behavioral model: Emotional disturbance arising from
or stimuli • Avoidance ... maladaptive beliefs and anxiety ... Dysregulation of anxiety ... reduce obsessional anxiety ... ObsessiveCompulsive #PersonalityDisorder
Panic Disorder: Pathogenesis and clinical findings
Social Factors
 • Parenting and infant attachment
 • Childhood illness/abuse
 •
Experiential Avoidance ... • Avoidance of ... carrying anti-anxiety ... discomfort) #PanicDisorder ... #Anxiety #BehavioralDisorder
Schizotypal Personality Disorder (SPD): Pathogenesis and clinical findings
Cognitive-Perceptual
 • Magical thinking - Belief in paranormal or
anhedonia • Social Anxiety ... reference - Anxiety ... #Schizotypal #PersonalityDisorder ... Diagnosis #Psychiatry #Criteria
Avoidant Personality Disorder (AVPD): Pathogenesis and Clinical Findings
 • Restraint - Shows excessive restraint in intimate
Avoidant Personality ... inferior #AVPD #Avoidant ... #PersonalityDisorder ... Diagnosis #Psychiatry #Criteria
Borderline Personality Disorder: Pathogenesis and Clinical Findings
Behavioral Traits:
 • Unstable Relationships - Alternating extremes of idealization
/ irritability/anxiety ... BPD #Borderline #PersonalityDisorder ... Diagnosis #Psychiatry #Criteria
Dependent Personality Disorder (DPD): Pathogenesis and Clinical Findings
 • Difficulties with Activities - Initiation Of projects
themselves • Avoidance ... DPD #Dependent #PersonalityDisorder ... Diagnosis #Psychiatry #Criteria
Social Anxiety Disorder (SAD) - Pathophysiology 
Excessive fear of one or more social situations
 • Safety
Social Anxiety Disorder ... Behaviors and Avoidance ... reduce social anxiety ... Panic Attacks, avoidance ... SocialAnxiety #BehavioralDisorder
Oppositional Defiant Disorder (ODD): Pathogenesis and clinical findings
 - Must have >4 symptoms for >6 months,
develop mood and anxiety ... OppositionalDefiant #ODD #BehavioralDisorder ... signs #psychiatry #criteria