The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Borderline Personality Disorder: Pathogenesis and Clinical Findings
Behavioral Traits:
 • Unstable Relationships - Alternating extremes of idealization
instability - Suicide ... PersonalityDisorder #Diagnosis ... #Psychiatry #Criteria ... #Signs #Symptoms ... #Mnemonic #AMSUICIDE
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
IgA Vasculitis – ... nephrotic/nephritic syndrome ... and ankles) #HSP ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Systemic Lupus Erythematosus: Gastrointestinal Manifestations
 - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
the pancreas, Vasculitis ... - Budd Chiari Syndrome ... pathophysiology #signs ... #symptoms #diagnosis
Major Depressive Disorder (MDD): Pathogenesis and Clinical Findings

Symptoms (included in DSM 5 criteria) - Present during
included in DSM 5 criteria ... thoughts of death or suicide ... MoodDisorders #Diagnosis ... Pathophysiology #Signs
Rheumatoid arthritis (RA): Extra-articular manifestations
Skin: 
 • Inflammation of skin (esp. over areas of stress) forms
Inflammation of skin (esp ... blood vessels (vasculitis ... blood to limbs (esp ... pathophysiology #signs ... #symptoms #diagnosis
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings
 - For diagnosis, must have either 26
findings - For diagnosis ... to 25 for new diagnosis ... AttentionDeficitHyperactiveDisorder #ADHD #BehavioralDisorder ... #symptoms #signs ... #psychiatry #criteria
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings
Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
primarily deltoids and hip ... Polymyositis #PM #Diagnosis ... Pathophysiology #Signs ... #Symptoms #Vasculitis
Kawasaki Disease: Clinical Findings
Diagnostic Criteria - Fever and 4/5 of the following:
 • Conjunctivitis
 • Polymorphous
Clinical Findings Diagnostic ... Criteria - Fever ... hands & feet Signs ... #Signs #Symptoms ... #Vasculitis
Chronic Exertional Compartment Syndrome (CECS)
 • Diagnosis Of CECS requires patient to undergo the same exertional
Exertional Compartment Syndrome ... (CECS) • Diagnosis ... • Diagnostic ... criteria for CECS ... #signs #symptoms
Serotonin Syndrome: Pathogenesis and Clinical Findings
Serotonin Syndrome: Variable combination of mental status changes, autonomic instability, and
Serotonin Syndrome ... muscle rigidity (esp ... Serotonin Toxicity Criteria ... make a clinical diagnosis ... #Signs #Symptoms