The Calgary Guide to Understanding Disease @TheCalgaryGuide
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First Generation Anti-Psychotics: Mechanisms and Side Effects
Typical/Conventional Anti-Psychotics - Examples: Haloperidol, Chlorpromazine

ACh M1 antagonist - Block
Anti-Psychotics: Mechanisms ... , and/or limbs caused ... AntiPsychotics #FirstGeneration ... #Mechanisms #SideEffects ... #pharmacology #diagnosis
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects
 • Serotonin Syndrome:
   - Autonomic Hyperactivity:
Reuptake Inhibitors: Mechanisms ... Dizziness - Nausea ... #Pharmacology #SideEffects ... #Psychiatry #Diagnosis
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Inhibitors(SNRIs): Mechanisms ... Diarrhea, Insomnia, Nausea ... gain Incr NE: Nausea ... #Pharmacology #SideEffects ... #Psychiatry #Diagnosis
Rheumatoid arthritis (RA): Extra-articular manifestations
Skin: 
 • Inflammation of skin (esp. over areas of stress) forms
blood vessels (vasculitis ... blood to limbs (esp ... inflammation tends to cause ... pulmonary fibrosis (mechanism ... signs #symptoms #diagnosis
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
IgA Vasculitis – ... periumbilical region), nausea ... and ankles) #HSP ... #IgA #Vasculitis ... Pathophysiology #Diagnosis
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
hair follicles -> causes ... inflammation (complex mechanism ... Livedo Reticularis, Vasculitis ... pathophysiology #diagnosis