The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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pathophysiology signs symptoms complications stages adhesivecapsulitis antipsychotics caudaequina cecs compartmentsyndrome disruptors firstgeneration fracture frozenshoulder lupus manifestations mechanisms mucocutaneous orthopedics pagetsdisease
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
exposed areas -> Scaring ... with keratotic scaling ... hair follicles -> causes ... Livedo Reticularis, Vasculitis ... pathophysiology #diagnosis
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings • Primary (Idiopathic): Unknown etiology, but associated
a stroke that caused ... post-inflammatory healing ... pathophysiology #diagnosis ... signs #stages #staging ... #msk
Chronic Exertional Compartment Syndrome (CECS) • Diagnosis Of CECS requires patient to undergo the same exertional
Syndrome (CECS) • Diagnosis ... activity that causes ... • Diagnostic ... pressure 0-4 mmHg #ChronicExertional ... signs #symptoms #msk
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Equina Syndrome Causes ... pain (shooting, stabbing ... CaudaEquina #Syndrome #MSK ... pathophysiology #diagnosis
First Generation Anti-Psychotics: Mechanisms and Side Effects Typical/Conventional Anti-Psychotics - Examples: Haloperidol, Chlorpromazine ACh M1 antagonist - Block
, and/or limbs caused ... • Akathisia - Feeling ... #SideEffects #pharmacology ... #diagnosis #psychiatry
Fracture Healing (and disruptors of this process) Inflammatory Stage (0-7d) • Fracture disrupts local blood vessels ->
Fracture Healing ... Fluoroquinolones - Causes ... #Orthopedics #msk ... #Staging #pathophysiology ... #diagnosis #disruptors
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Abnormal Osteoclasts cause ... bone formation MSK ... Skull expansion causes ... -> Conductive hearing ... pathophysiology #diagnosis
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