The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
Stevens-Johnson Syndrome ... Dermatitis (ie. reaction ... #Allergic #Reactions ... #Types #Classification ... #Diagnosis #Definitions
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
cell surfaces causes ... An allergic reaction ... #Allergic #Reactions ... #Types #Classification ... #Diagnosis #Definitions
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
constipation • Allergic ... reaction -> Benign ... Stevens-Johnson Syndrome ... Systemic effect -> Nausea ... Pathophysiology #Psychiatry
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings
 - For diagnosis, must have either 26
findings - For diagnosis ... to 25 for new diagnosis ... their turn • Causes ... Pathophysiology #diagnosis ... #psychiatry #criteria
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects
 • Serotonin Syndrome:
   - Autonomic Hyperactivity:
• Serotonin Syndrome ... Dizziness - Nausea ... #SideEffects #Psychiatry ... #Diagnosis #Signs ... #Symptoms
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Vomiting Serotonin Syndrome ... gain Incr NE: Nausea ... #SideEffects #Psychiatry ... #Diagnosis #Signs ... #Symptoms
Serotonin Syndrome: Pathogenesis and Clinical Findings
Serotonin Syndrome: Variable combination of mental status changes, autonomic instability, and
ingestion and most cases ... make a clinical diagnosis ... Pathophysiology #Psychiatry ... #Diagnosis #Signs ... #Symptoms
Bulimia Nervosa: Complications
GASTROINTESTINAL
 • Dehydration & inability to digest food -> Constipation
 • Recurrent vomiting exposes
• Boerhaave syndrome ... hormone levels cause ... pathophysiology #diagnosis ... #signs #symptoms ... #psychiatry