The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology signs symptoms behavioraldisorder pharmacology sideeffects complications criteria allergic bulimianervosa definitions hypersensitivity inhibitors mnemonic reactions retinopathy serotonin types adhd alcoholusedisorder
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Immunological Target: Allergen ... fever, Urticaria, Allergic ... #Allergic #Reactions ... #Types #Classification ... #Diagnosis #Definitions
Hypersensitivity: Definitions • Type I - Production of lgE Abs that bind to harmless allergens and
leading to an allergic ... cell surfaces causes ... causes development ... #Types #Classification ... #Diagnosis #Definitions
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect Examples: Valproate, Carbamazepine, Lamotrigine • Mild anticholinergic effect -> Drowsiness
constipation • Allergic ... Systemic effect -> Nausea ... Pathophysiology #Psychiatry
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting Serotonin Syndrome - Potentially Life
Diarrhea, Insomnia, Nausea ... gain Incr NE: Nausea ... #SideEffects #Psychiatry ... #Diagnosis #Signs
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects • Serotonin Syndrome: - Autonomic Hyperactivity:
Dizziness - Nausea ... #SideEffects #Psychiatry ... #Diagnosis #Signs
Schizophrenia: Pathogenesis and Symptoms Increased dopaminergic transmission in mesolimbic projection -> Dopaminergic neurons here project into the limbic
is thought to cause ... is thought to cause ... pathophysiology #diagnosis ... symptoms #signs #psychiatry
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings Ophthalmic Artery Hypertension Stage 1: Mild/vasoconstrictive • Acute and chronic vasospasm
hyalinization causes ... BRB breakdown causes ... disc arterioles causes ... pathophysiology #ophthalmology ... #diagnosis #signs
Alcohol Use Disorder: Pathogenesis and Clinical Findings • Tolerance (reduced sensitivity to effects of EtOH) •
, tachycardia, nausea ... Pathophysiology #Diagnosis ... Signs #Symptoms #Psychiatry
First Generation Anti-Psychotics: Mechanisms and Side Effects Typical/Conventional Anti-Psychotics - Examples: Haloperidol, Chlorpromazine ACh M1 antagonist - Block
, and/or limbs caused ... #pharmacology #diagnosis ... #psychiatry
Diabetic Retinopathy: Pathogenesis and clinical findings Mild Non-proliferative DR • Outpouchings of the weakened capillary walls or
retinal ischemia causes ... Retinopathy #Diabetes #ophthalmology ... #diagnosis #complications
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