The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects
 • Serotonin Syndrome:
   - Autonomic Hyperactivity:
Hyperactivity: Hypertension ... Pathophysiology #Pharmacology ... SideEffects #Psychiatry #Diagnosis ... #Signs #Symptoms
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Hyperactivity: Hypertension ... Pathophysiology #Pharmacology ... SideEffects #Psychiatry #Diagnosis ... #Signs #Symptoms
Central Retinal Vein Occlusion (CRVO): Pathogenesis and clinical findings

#CentralRetinalVein #Occlusion #CRVO #pathophysiology #ophthalmology #diagnosis #signs #symptoms
pathophysiology #ophthalmology ... #diagnosis #signs ... #symptoms
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
Chronic Hypertensive ... Ophthalmic Artery Hypertension ... pathophysiology #ophthalmology ... #diagnosis #signs ... #symptoms #complications
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Retinoblastoma Signs / Symptoms ... pathophysiology #ophthalmology ... #diagnosis #signs ... #symptoms
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings

Medical Comorbidities Malignancies (most commonly hairy-cell leukemia)
Immunogenetic Predisposition: patient is
- Malignant Hypertension ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Xeropthalmia: Pathogenesis and Ocular Manifestations

Decr Visual pigment -> Keratinization, thickening & non-wetting of the conjunctiva
pathophysiology #ophthalmology ... #diagnosis #signs ... #symptoms
Orbital Cellulitis: Pathogenesis and Clinical Findings
Definitions:
a. Chemosis: Edema of the bulbar conjunctiva
b. Panopthalmitis: inflammation of all
pathophysiology #ophthalmology ... #diagnosis #signs ... #symptoms
First Generation Anti-Psychotics: Mechanisms and Side Effects
Typical/Conventional Anti-Psychotics - Examples: Haloperidol, Chlorpromazine

ACh M1 antagonist - Block
Extrapyramidal Symptoms ... #SideEffects #pharmacology ... #diagnosis #psychiatry
Periorbital Cellulitis: Pathogenesis and Clinical Findings
Definitions:
a. Dacryoadenitis: infection of the lacrimal glands
b. Conjunctivitis: inflammation of the
pathophysiology #ophthalmology ... #diagnosis #signs ... #symptoms