The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Alcohol Use Disorder: Pathogenesis and Clinical Findings

 • Tolerance (reduced sensitivity to effects of EtOH)
 •
Alcohol Use Disorder ... • Withdrawal symptoms ... , seizure, and anxiety ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects
 • Serotonin Syndrome:
   - Autonomic Hyperactivity:
Hyperactivity: Hypertension ... Pathophysiology #Pharmacology ... SideEffects #Psychiatry #Diagnosis ... #Signs #Symptoms
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Hyperactivity: Hypertension ... Pathophysiology #Pharmacology ... SideEffects #Psychiatry #Diagnosis ... #Signs #Symptoms
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
Chronic Hypertensive ... Ophthalmic Artery Hypertension ... pathophysiology #ophthalmology ... #diagnosis #signs ... #symptoms #complications
Panic Disorder: Pathogenesis and clinical findings
Social Factors
 • Parenting and infant attachment
 • Childhood illness/abuse
 •
exercise, caffeine, alcohol ... carrying anti-anxiety ... Anticipatory Anxiety ... Pathophysiology #diagnosis ... #symptoms #signs
Opioid Withdrawal: Clinical Findings and Complications
Note: Opioid withdrawal can be extremely uncomfortable, but is rarely life-threatening
withdrawal of alcohol ... Symptoms can take ... Dysphoric mood, anxiety ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Social Anxiety Disorder (SAD) - Pathophysiology 
Excessive fear of one or more social situations
 • Safety
Social Anxiety Disorder ... > • Drug and Alcohol ... of Anxiety: Mind ... Pathophysiology #diagnosis ... #symptoms #signs
Alcohol Withdrawal: Clinical Findings and Complications
The onset of alcohol withdrawal generally begins 6-24 hours after the
Alcohol Withdrawal ... - Tachycardia, hypertension ... - Anxiety, insomnia ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Serotonin Syndrome: Pathogenesis and Clinical Findings
Serotonin Syndrome: Variable combination of mental status changes, autonomic instability, and
Mental Status - Anxiety ... tachycardia, mydriasis, hypertension ... make a clinical diagnosis ... Pathophysiology #Psychiatry #Diagnosis ... #Signs #Symptoms