The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology signs symptoms psychiatry complications orthopedics acquired acs acute anorexianervosa bonestrength causes compartmentsyndrome disorders endocrinology femur gh growthhormone msk osteomalacia
Subtrochanteric Femur Fracture: Pathogenesis and clinical findings • Subtrochanteric region spans 5 cm distally from the
Subtrochanteric Femur Fracture ... low energy fall fractures ... Major trauma -> An excess ... #orthopedics #diagnosis ... #differential #
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
Growth Hormone Excess ... GH excess prior ... Carpal Tunnel Syndrome ... Acne • Coarse features ... Overproduction #diagnosis
Acute Compartment Syndrome • Crush injuries, burns, circumferential constriction to limbs (each containing facially divided muscle
Acute Compartment Syndrome ... bleeding tendency/fracture ... disperse. => Excess
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features • RA affects 1% of population, women >
Joint diseases features ... joint capsule exceeds ... signs #symptoms #diagnosis
Bulimia Nervosa: Signs and Symptoms Associated Psychological / Behavioural Features • Feelings of shame, guilt and embarrassment
/ Behavioural Features ... Problems and Facial Features ... inducing vomiting #BulimiaNervosa ... pathophysiology #diagnosis
Rickets and Osteomalacia: Pathogenesis and Clinical Findings • Calcification inhibitors (excess exposure to A1, Fluoride, etidronate)
Calcification inhibitors (excess ... Bowed legs • Fractures ... pathophysiology #diagnosis
Anorexia Nervosa: Complications CARDIAC ABNORMALITIES - Functional: Low BP, Sinus bradycardia, prolonged QT interval - Structural: Reduced
increased risk of fracture ... warmth) GENERAL FEATURES ... - Lethargy or Excess ... pathophysiology #diagnosis
Bulimia Nervosa: Complications GASTROINTESTINAL • Dehydration & inability to digest food -> Constipation • Recurrent vomiting exposes
• Boerhaave syndrome ... Cardiac Arrest #BulimiaNervosa ... pathophysiology #diagnosis
Acquired Disorders of Reduced Bone Strength: Pathogenesis • Hyperparathyroidism • Vitamin D deficiency • Malabsorption syndromes
Malabsorption syndromes ... pathophysiology #differential ... #diagnosis #osteoporosis
Serotonin Syndrome: Pathogenesis and Clinical Findings Serotonin Syndrome: Variable combination of mental status changes, autonomic instability, and
Serotonin Syndrome ... Findings Serotonin Syndrome ... make a clinical diagnosis ... following clinical features ... Pathophysiology #Psychiatry #Diagnosis
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