The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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pathophysiology symptoms staging adhesivecapsulitis bonestrength complications disruptors fracture frozenshoulder healing orthopedics osteoporosis pagetsdisease psychiatry sedondary serotonin
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings • Primary (Idiopathic): Unknown etiology, but associated
with autoimmune disorders ... , humeral head fracture ... a stroke that caused ... #symptoms #signs ... #msk
Acquired Disorders of Reduced Bone Strength: Pathogenesis • Hyperparathyroidism • Vitamin D deficiency • Malabsorption syndromes
Acquired Disorders ... Malabsorption syndromes ... Diabetes • Other causes ... pathophysiology #differential ... #diagnosis #osteoporosis
Fracture Healing (and disruptors of this process) Inflammatory Stage (0-7d) • Fracture disrupts local blood vessels ->
Inflammatory Stage ... Metabolic / Endocrine disorders ... Fluoroquinolones - Causes ... #msk #Staging # ... pathophysiology #diagnosis
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
bone formation MSK ... -> Pathologic fractures ... Nerve Palsies • Disordered ... pathophysiology #diagnosis ... #signs #symptoms
Serotonin Syndrome: Pathogenesis and Clinical Findings Serotonin Syndrome: Variable combination of mental status changes, autonomic instability, and
combination of mental status ... ingestion and most cases ... Altered Mental Status ... make a clinical diagnosis ... #Signs #Symptoms
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