The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology psychiatry sideeffects signs symptoms mechanisms complications inhibitors retinopathy centralretinalartery chronic crao diabetes diabetic differential firstgeneration hypertensive mania manic occlusion
Third Generation Antipsychotics: Mechanisms and Side Effects (Atypical Anti-Psychotics) Example: Aripiprazole Dopamine D2 Receptor Partial Agonist • Binds
Third Generation Antipsychotics ... under-stimulating receptors Serotonin ... Antidepressant Effects #AntiPsychotics ... #SideEffects #pharmacology ... #diagnosis #psychiatry
Second Generation Antipsychotics: Mechanisms and Side Effects (Atypical Anti-Psychotics) - Examples: Clozapine, Olanzapine, Quetiapine, Risperidone, Zotepine, Paliperidone,
Second Generation Antipsychotics ... the brain • Serotonin ... the brain • Serotonin ... #SideEffects #pharmacology ... #diagnosis #psychiatry
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects • Serotonin Syndrome: - Autonomic Hyperactivity:
Selective Serotonin ... Side Effects • Serotonin ... Dizziness - Nausea ... Pathophysiology #Pharmacology ... SideEffects #Psychiatry #Diagnosis
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting Serotonin Syndrome - Potentially Life
Serotonin-Norepinephrine ... , Vomiting Serotonin ... gain Incr NE: Nausea ... Pathophysiology #Pharmacology ... SideEffects #Psychiatry #Diagnosis
First Generation Anti-Psychotics: Mechanisms and Side Effects Typical/Conventional Anti-Psychotics - Examples: Haloperidol, Chlorpromazine ACh M1 antagonist - Block
, and/or limbs caused ... restlessness #AntiPsychotics ... #SideEffects #pharmacology ... #diagnosis #psychiatry
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings Ophthalmic Artery Hypertension Stage 1: Mild/vasoconstrictive • Acute and chronic vasospasm
hyalinization causes ... BRB breakdown causes ... disc arterioles causes ... pathophysiology #ophthalmology ... #diagnosis #signs
Diabetic Retinopathy: Pathogenesis and clinical findings Mild Non-proliferative DR • Outpouchings of the weakened capillary walls or
retinal ischemia causes ... Retinopathy #Diabetes #ophthalmology ... #diagnosis #complications
Medical Conditions Causing Mania or Mania-Like Episodes: Pathogenesis • Bipolar Disorder -> Combination of individual, genetic,
Decrased central serotonin ... Manic #Secondary #Causes ... #Differential #Diagnosis
Central Retinal Artery Occlusion: Pathogenesis and clinical findings • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
retinal edema caused ... pathophysiology #ophthalmology ... #diagnosis #signs
Serotonin Syndrome: Pathogenesis and Clinical Findings Serotonin Syndrome: Variable combination of mental status changes, autonomic instability, and
Serotonin Syndrome ... Clinical Findings Serotonin ... ingestion and most cases ... make a clinical diagnosis ... Pathophysiology #Psychiatry #Diagnosis
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