The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology symptoms psychiatry msk pharmacology etoh inhibitors serotonin acute alcohol alcoholusedisorder alzheimersdisease anticonvulsants caudaequina cecs chronicexertional compartmentsyndrome complications dementia endocrinology
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects • Serotonin Syndrome: - Autonomic Hyperactivity:
Akathisia • SSRI Withdrawal ... Dizziness - Nausea ... #Pharmacology #SideEffects ... #Psychiatry #Diagnosis ... #Signs #Symptoms
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting Serotonin Syndrome - Potentially Life
Side Effects Withdrawal ... Vomiting Serotonin Syndrome ... #Pharmacology #SideEffects ... #Psychiatry #Diagnosis ... #Signs #Symptoms
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect Examples: Valproate, Carbamazepine, Lamotrigine • Mild anticholinergic effect -> Drowsiness
Stevens-Johnson Syndrome ... decr intake -> Withdrawal ... Systemic effect -> Nausea ... MoodStabilizers #Mechanism #SideEffects
Acute Spinal Cord Injuries: Pathogenesis and clinical findings • Anterior Cord Syndrome -> Anterior spinal artery
Anterior Cord Syndrome ... • Central Cord Syndrome ... #diagnosis #pathophysiology ... #signs #symptoms ... #orthopedics #neurology
Alzheimer’s Disease: Pathogenesis and Clinical Findings Risk factor for Late Onset Alzheimer's (99% of cases): - Increasing
Alzheimer's (99% of cases ... mutations - Down syndrome ... chromosome 21) Signs ... pathophysiology #geriatrics #diagnosis ... #signs #symptoms
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Cauda Equina Syndrome ... Causes: • Large ... lumbar spine Signs ... pathophysiology #diagnosis ... #symptoms #signs
Opioid Withdrawal: Clinical Findings and Complications Note: Opioid withdrawal can be extremely uncomfortable, but is rarely life-threatening
Opioid Withdrawal ... Note: Opioid withdrawal ... Gastrointestinal distress (nausea ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Alcohol Use Disorder: Pathogenesis and Clinical Findings • Tolerance (reduced sensitivity to effects of EtOH) •
to use EtOH • Withdrawal ... , tachycardia, nausea ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
• Other rare causes ... Carpal Tunnel Syndrome ... Overproduction #diagnosis ... #signs #symptoms
Bulimia Nervosa: Signs and Symptoms Associated Psychological / Behavioural Features • Feelings of shame, guilt and embarrassment
Bulimia Nervosa: Signs ... Sores, scars, calluses ... inducing vomiting #BulimiaNervosa ... pathophysiology #diagnosis ... #signs #symptoms
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