The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology signs symptoms complications sle agammaglobulinemia allergy avascularnecrosis erythematosus hypersensitivityreaction incontinence manifestations mastoiditis mixed msk mucocutaneous musculoskeletal otology systemic type3
Type III Hypersensitivity: Pathogenesis and clinical findings Definition: Small antigen-antibody complexes (produced from normal immune response to
self-antigens are the cause ... : • Systemic Lupus ... antigens are the cause ... HypersensitivityReaction #Allergy #Immunology
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... Myopathy (Also caused ... #Systemic #Lupus ... signs #symptoms #diagnosis
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Subacute cutaneous lupus ... hair follicles -> causes ... Phenomenon #Lupus ... pathophysiology #diagnosis
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings The epidemiology of this disease is 1/340,000 births and roughly double
40% of patients diagnosed ... to produce all classes ... pathophysiology #immunology
Mixed Urinary Incontinence: Pathogenesis and Clinical Findings Urgency Urinary Incontinence (UUI) -> Urinary leakage preceded by a
SUI or UUI not caused ... Signs #Symptoms #Urology ... #Diagnosis
Varicocele: Pathogenesis and clinical findings Primary: - Anatomically: the left spermatic vein drains into the left renal
retroperitoneal masses ... Signs #Symptoms #Urology ... #Diagnosis
Mastoiditis: Pathogenesis and clinical findings Acute or Chronic Otitis Media -> Stage 1: Hyperemeia of the mastoid
hearing loss, nausea ... signs #symptoms #diagnosis ... #otology
Avascular Necrosis: Pathogenesis and Clinical Findings • Physical Trauma (esp. to the scaphoid bone with damage
) • Multiple causes ... therapy - Lupus ... pathophysiology #diagnosis
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