The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Subtrochanteric Femur Fracture: Pathogenesis and clinical findings
 • Subtrochanteric region spans 5 cm distally from the
Subtrochanteric Femur Fracture ... low energy fall fractures ... in elderly Causes ... #orthopedics #diagnosis ... #differential #causes
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Acute Spinal Cord ... Anterior Cord Syndrome ... weakness and #Acute ... #diagnosis #pathophysiology ... #orthopedics #neurology
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
• Other rare causes ... Carpal Tunnel Syndrome ... Acne • Coarse features ... Overproduction #diagnosis
Acute Compartment Syndrome
 • Crush injuries, burns, circumferential constriction to limbs (each containing facially divided muscle
Acute Compartment ... Syndrome • Crush ... bleeding tendency/fracture ... compartment pressure #Acute
Systemic Lupus Erythematosus: Gastrointestinal Manifestations
 - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Vasculitis -> Acute ... - Budd Chiari Syndrome ... signs #symptoms #diagnosis
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects
 • Serotonin Syndrome:
   - Autonomic Hyperactivity:
• Serotonin Syndrome ... SSRI Withdrawal Syndrome ... Dizziness - Nausea ... SideEffects #Psychiatry #Diagnosis
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Diarrhea, Insomnia, Nausea ... Vomiting Serotonin Syndrome ... gain Incr NE: Nausea ... SideEffects #Psychiatry #Diagnosis
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
vasoconstrictive • Acute ... hyalinization causes ... BRB breakdown causes ... disc arterioles causes ... ophthalmology #diagnosis
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Cauda Equina Syndrome ... Causes: • Large ... #CaudaEquina #Syndrome ... pathophysiology #diagnosis
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Alzheimer's (99% of cases ... Alzheimer's (1% of cases ... mutations - Down syndrome ... pathophysiology #geriatrics #diagnosis