The Calgary Guide to Understanding Disease @TheCalgaryGuide
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signs symptoms psychiatry msk complications behavioraldisorder differential immunology ophthalmology orthopedics pharmacology sideeffects bulimianervosa criteria etoh hypersensitivityreaction inhibitors lupus serotonin sle
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
mediated; exposure to allergen ... causes development ... of allergen-specific ... Allergic reaction ... #Immunology #pathophysiology
Type III Hypersensitivity: Pathogenesis and clinical findings Definition: Small antigen-antibody complexes (produced from normal immune response to
self-antigens are the cause ... antigens are the cause ... HypersensitivityReaction #Allergy ... #Immunology #pathophysiology
Diabetic Retinopathy: Pathogenesis and clinical findings Mild Non-proliferative DR • Outpouchings of the weakened capillary walls or
Diabetic Retinopathy ... retinal ischemia causes ... #Diabetic #Retinopathy ... ophthalmology #diagnosis ... complications #pathophysiology
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings Ophthalmic Artery Hypertension Stage 1: Mild/vasoconstrictive • Acute and chronic vasospasm
Chronic Hypertensive Retinopathy ... hyalinization causes ... #Hypertensive #Retinopathy ... #pathophysiology ... ophthalmology #diagnosis
Subjective Tinnitus: Pathogenesis and clinical findings Subjective Tinnitus - Perceived sound with no acoustic stimulus, heard only
refers to sound caused ... #Tinnitus #Causes ... #pathophysiology ... #differential #diagnosis
Xeropthalmia: Pathogenesis and Ocular Manifestations Decr Visual pigment -> Keratinization, thickening & non-wetting of the conjunctiva
focal melting) -> Retinopathy ... #Xeropthalmia #pathophysiology ... ophthalmology #diagnosis
Hypersensitivity: Definitions • Type I - Production of lgE Abs that bind to harmless allergens and
leading to an allergic ... cell surfaces causes ... leading to an allergic ... causes development ... Classification #Diagnosis
Anaphylaxis: Signs and Symptoms Anaphylaxis: when any egg of three conditions is met: 1. Acute onset of skin/mucosal
exposure to a likely allergen ... exposure to known allergen ... #Anaphylaxis #pathophysiology ... #immunology #diagnosis
Septic Arthritis: Pathogenesis and clinical findings Notes: - Septic Arthritis is typically monoarticular & the knee is involved
involved in >50% of cases ... S.A. can also be caused ... SepticArthritis #pathophysiology ... #diagnosis
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect Examples: Valproate, Carbamazepine, Lamotrigine • Mild anticholinergic effect -> Drowsiness
constipation • Allergic ... Systemic effect -> Nausea ... #SideEffects #Pathophysiology
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