The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Dupuytren’s Disease: Pathogenesis and Clinical Findings
 • Aging, smoking and/or diabetes -> Microangiopathy and palmar fascia
Dupuytren’s Disease ... Clinical Findings • Aging ... smoking and/or diabetes ... #Contractures #pathophysiology ... #msk
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings

 • Primary (Idiopathic): Unknown etiology, but associated
autoimmune disorders (diabetes ... , humeral head fracture ... side) Second Stage ... FrozenShoulder #pathophysiology ... #staging #msk
Fracture Healing (and disruptors of this process)
Inflammatory Stage (0-7d)
 • Fracture disrupts local blood vessels ->
Inflammatory Stage ... site Soft Callus Stage ... #Stages #Orthopedics ... #msk #Staging # ... pathophysiology
Paget’s Disease: Complications
Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation

MSK
Paget’s Disease: Complications ... bone formation MSK ... -> Pathologic fractures ... Nephrolithiasis (Kidney Stones ... PagetsDisease #pathophysiology