The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology symptoms diagnosis genetics geriatrics pediatrics peds syndrome urinarytractinfection 21hydroxylasedeficiency 21ohd alzheimersdisease ankylosingspondylitis bulimianervosa caudaequina dementia diabeticketoacidosis dka extraarticular fecal
Fecal Incontinence - Pathogenesis and Complications Continence mechanisms are impaired • Local neuronal damage • External and
Fecal Incontinence ... Pathogenesis and Complications ... Continence mechanisms ... Diabetes) • Altered ... #Fecal #stool #Incontinence
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
Pituitary Mass Effects ... Signs / Symptoms ... / Complications ... Hyperprolactinemia • Diabetes ... #SideEffects #endocrinology
Mixed Urinary Incontinence: Pathogenesis and Clinical Findings Urgency Urinary Incontinence (UUI) -> Urinary leakage preceded by a
Mixed Urinary Incontinence ... Urgency Urinary Incontinence ... cystitis, UTI), diabetes ... Incr PVR if a complication ... Pathophysiology #Signs
Primary Hyperthyroidism - Pathogenesis and Clinical Findings Note: Although rare, gestational diseases can lead to thyrotoxicosis due
production by the pituitary ... Signs/Symptoms: ... Hyperthyroidism #endocrinology
Alzheimer’s Disease: Pathogenesis and Clinical Findings Risk factor for Late Onset Alzheimer's (99% of cases): - Increasing
chromosome 21) Signs ... / Symptoms / Complications ... primitive reflexes, incontinence ... geriatrics #diagnosis #signs
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates lipolysis Signs ... #FeedbackLoop #endocrinology ... pathophysiology #pituitary
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
lumbar spine Signs ... / Symptoms / Complications ... retention -> Overflow Incontinence ... diagnosis #symptoms #signs
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings • Note: in DKA, body K+ is lost
Diabetic Ketoacidosis ... Signs/Symptoms/Complications ... pathophysiology #endocrinology ... #diabetes
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome Signs ... /Symptoms/Complications ... Obesity -> Type 2 diabetes
Lower Urinary Tract Infection: Pathogenesis and Clinical Findings - Predisposing Factors: Immunocompromised state, diabetes, elderly, female
Immunocompromised state, diabetes ... causing symptoms Signs ... quickly or impending incontinence ... Pathophysiology #Signs
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