The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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pathophysiology diagnosis menstrualcycle signs symptoms ovariancycle ophthalmology pituitary complications diabetic feedbackloop genetics growthhormone incontinence msk pediatrics peds urinarytractinfection urology uterinecycle
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
following order; GH ... Hyperprolactinemia • Diabetes ... #SideEffects #endocrinology
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... /Symptoms: • GH ... abn lipid • GH ... GrowthHormone #GH ... #FeedbackLoop #endocrinology
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
time of onset of GH ... GH excess prior ... GH excess after ... GrowthHormone #GH ... signs #symptoms #endocrinology
Diabetic Nephropathy: Pathogenesis - Metabolic Pathway - Hemodynamic Pathway #Diabetic #Nephropathy #Diabetes #pathophysiology
Diabetic Nephropathy ... Hemodynamic Pathway #Diabetic ... #Nephropathy #Diabetes
Erectile Dysfunction: Pathogenesis Erectile Dysfunction - Persistent or recurrent inability to achieve an erection sufficient to achieve
trauma, iatrogenic, diabetes ... and rigidity Endocrinologic ... hyperlipidemia, diabetes ... (penile artery diameter
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings • Note: in DKA, body K+ is lost
Diabetic Ketoacidosis ... pathophysiology #endocrinology ... #diabetes
Diabetic Retinopathy: Pathogenesis and clinical findings Mild Non-proliferative DR • Outpouchings of the weakened capillary walls or
Diabetic Retinopathy ... Neovascularization #Diabetic ... #Retinopathy #Diabetes
Diabetic Foot: Pathogenesis and clinical findings • Polyol Pathway - Excess glucose enters Polyol pathway ->
Diabetic Foot: Pathogenesis ... neuropathy => Diabetic ... a person with diabetes ... complications #Diabetes
Graves’ Disease: Pathogenesis and Clinical Findings B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
pathophysiology #endocin #endocrinology
Primary Hyperthyroidism - Pathogenesis and Clinical Findings Note: Although rare, gestational diseases can lead to thyrotoxicosis due
Hyperthyroidism #endocrinology
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