The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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pathophysiology antipsychotics pharmacology psychiatry sideeffects msk orthopedics radiology xray benign classification complications diabetes diabeticketoacidosis disruptors dysfunction erectile features firstgeneration fracture
Malignant Bone Tumors: Pathogenesis of X-ray appearance • Metastatic bone tumors (aka. cancerous cells from systemic
Malignant Bone Tumors ... • Metastatic bone ... tumors (aka. cancerous ... tumor #BoneTumors ... Malignant #Radiology #Diagnosis
Second Generation Antipsychotics: Mechanisms and Side Effects (Atypical Anti-Psychotics) - Examples: Clozapine, Olanzapine, Quetiapine, Risperidone, Zotepine, Paliperidone,
Antipsychotics: Mechanisms ... Block action of DA ... action throughout body ... SecondGeneration #Mechanisms ... #pharmacology #diagnosis
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings • Note: in DKA, body K+ is lost
Ketoacidosis (DKA ... Findings • Note: in DKA ... , body K+ is lost ... brain... thus, the body ... pathophysiology #endocrinology
Third Generation Antipsychotics: Mechanisms and Side Effects (Atypical Anti-Psychotics) Example: Aripiprazole Dopamine D2 Receptor Partial Agonist • Binds
Antipsychotics: Mechanisms ... Prevents excess DA ... and deficient DA ... ThirdGeneration #Mechanisms ... #pharmacology #diagnosis
Open Fractures: Mechanisms, Clinical Features and Complications Gustilo-Anderson Classification: • Type I - Wound <
Open Fractures: Mechanisms ... soft tissue for bone ... Open #Fractures #Diagnosis
Benign Primary Bone Tumors: Pathogenesis of X-ray appearance • "Geographic" bone destruction • Lack of soft-tissue
Benign Primary Bone ... • "Geographic" bone ... periosteum) #Benign #BoneTumors ... #XRay #diagnosis
First Generation Anti-Psychotics: Mechanisms and Side Effects Typical/Conventional Anti-Psychotics - Examples: Haloperidol, Chlorpromazine ACh M1 antagonist - Block
Anti-Psychotics: Mechanisms ... ACh throughout body ... FirstGeneration #Mechanisms ... #pharmacology #diagnosis
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features • RA affects 1% of population, women >
in subchondral bone ... and subcondral bone ... inflammation + other mechanisms ... signs #symptoms #diagnosis
Erectile Dysfunction: Pathogenesis Erectile Dysfunction - Persistent or recurrent inability to achieve an erection sufficient to achieve
disorder -> Possible mechanisms ... and rigidity Endocrinologic ... Pathophysiology #Urology #Diagnosis
Fracture Healing (and disruptors of this process) Inflammatory Stage (0-7d) • Fracture disrupts local blood vessels ->
osteoblasts forms bony ... Osteoclast-osteoblast coupled bone ... healing time, mechanisms ... from GI tract, bone ... pathophysiology #diagnosis
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