The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Malignant Bone Tumors: Clinical Findings and Complications

#Malignant #BoneTumors #Bony #Complications #pathophysiology
Malignant Bone Tumors ... #Malignant #BoneTumors ... #Bony #Complications ... #pathophysiology
Malignant Bone Tumors: Pathogenesis of X-ray appearance

 • Metastatic bone tumors (aka. cancerous cells from systemic
Malignant Bone Tumors ... • Metastatic bone ... tumors (aka. cancerous ... • Metastatic bone ... tumor #BoneTumors
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
Ketoacidosis (DKA ... , body K+ is lost ... brain... thus, the body ... #pathophysiology ... #endocrinology
Menstrual Cycle Physiology: Ovarian Cycle – Brief Overview
LH and FSH are required for follicular development and
MenstrualCycle #OvarianCycle ... #pathophysiology ... #menstruation #endocrinology
Menstrual Cycle Physiology: Ovarian Cycle – Ovulation Explained

Around Day 14, estrogen exerts sudden +++ positive feedback
MenstrualCycle #OvarianCycle ... #pathophysiology ... #Ovulation #endocrinology
Menstrual Cycle Physiology: Ovarian Cycle – Luteal Phase Explained
 • The LH surge can be thought
MenstrualCycle #OvarianCycle ... #pathophysiology ... #LutealPhase #endocrinology
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Incr IGF1 • Bone ... #FeedbackLoop #endocrinology ... #pathophysiology
Menstrual Cycle Physiology: Correlating the Ovarian and Uterine Cycles
Note: Some charts show different relative levels of
MenstrualCycle #OvarianCycle ... #pathophysiology ... #comparison #endocrinology
Menstrual Cycle Physiology: Ovarian Cycle – Follicular Phase Explained
Early Follicular Phase (Days 0-5)
 • Granulosa cells
MenstrualCycle #OvarianCycle ... #pathophysiology ... FollicularPhase #endocrinology
Menstrual Cycle Physiology: the Uterine Cycle
The endometrium has receptors for ovarian hormones! Changes in structure and
MenstrualCycle #OvarianCycle ... #pathophysiology ... #UterineCycle #endocrinology