The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... /Symptoms: • GH ... abn lipid • GH ... metabolic abn #GrowthHormone ... #endocrinology
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
GH excess prior ... GH excess after ... fraction • HTN #GrowthHormone ... #diagnosis #signs ... #symptoms #endocrinology
Third Generation Antipsychotics: Mechanisms and Side Effects
(Atypical Anti-Psychotics) Example: Aripiprazole
Dopamine D2 Receptor Partial Agonist
 • Binds
Prevents excess DA ... and deficient DA ... #pharmacology #diagnosis ... #psychiatry
Second Generation Antipsychotics: Mechanisms and Side Effects
(Atypical Anti-Psychotics) - Examples: Clozapine, Olanzapine, Quetiapine, Risperidone, Zotepine, Paliperidone,
Block action of DA ... #pharmacology #diagnosis ... #psychiatry