The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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pathophysiology antipsychotics diagnosis pharmacology psychiatry menstrualcycle ovariancycle comparison feedbackloop firstgeneration follicularphase glftap growthhormone macroadenoma masseffects mnemonic secondgeneration thirdgeneration uterinecycle
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... /Symptoms: • GH ... abn lipid • GH ... #FeedbackLoop #endocrinology ... pathophysiology #pituitary
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
Pituitary Mass Effects ... Pituitary adenomas ... following order; GH ... #Macroadenoma #SideEffects ... #endocrinology
Third Generation Antipsychotics: Mechanisms and Side Effects (Atypical Anti-Psychotics) Example: Aripiprazole Dopamine D2 Receptor Partial Agonist • Binds
Antipsychotics: Mechanisms ... Prevents excess DA ... and deficient DA ... ThirdGeneration #Mechanisms ... #SideEffects #pharmacology
Second Generation Antipsychotics: Mechanisms and Side Effects (Atypical Anti-Psychotics) - Examples: Clozapine, Olanzapine, Quetiapine, Risperidone, Zotepine, Paliperidone,
Antipsychotics: Mechanisms ... Block action of DA ... Cardio-metabolic effects - Mechanism ... SecondGeneration #Mechanisms ... #SideEffects #pharmacology
Menstrual Cycle Physiology: Ovarian Cycle – Follicular Phase Explained Early Follicular Phase (Days 0-5) • Granulosa cells
production by pituitary ... back on anterior pituitary ... continue growing (mechanism ... growth (this is one mechanism ... FollicularPhase #endocrinology
First Generation Anti-Psychotics: Mechanisms and Side Effects Typical/Conventional Anti-Psychotics - Examples: Haloperidol, Chlorpromazine ACh M1 antagonist - Block
Anti-Psychotics: Mechanisms ... Hypothalamus -> Pituitary ... FirstGeneration #Mechanisms ... #SideEffects #pharmacology
Menstrual Cycle Physiology: Correlating the Ovarian and Uterine Cycles Note: Some charts show different relative levels of
puberty (unclear mechanisms ... on the anterior pituitary ... pathophysiology #comparison #endocrinology
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