The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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pathophysiology diagnosis signs symptoms growthhormone mnemonic pituitary sideeffects anorexianervosa antipsychotics complications criteria feedbackloop glftap hyperthyroidism macroadenoma masseffects mechanisms narcissistic npd
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
time of onset of GH ... GH excess prior ... GH excess after ... GrowthHormone #GH ... signs #symptoms #endocrinology
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... /Symptoms: • GH ... abn lipid • GH ... excess: - ... #FeedbackLoop #endocrinology
Primary Hyperthyroidism - Pathogenesis and Clinical Findings Note: Although rare, gestational diseases can lead to thyrotoxicosis due
thyrotoxicosis due to excess ... hyperthyroidism due to excess ... Hyperthyroidism #endocrinology
Third Generation Antipsychotics: Mechanisms and Side Effects (Atypical Anti-Psychotics) Example: Aripiprazole Dopamine D2 Receptor Partial Agonist • Binds
• Prevents excess ... does not allow excess ... pharmacology #diagnosis #psychiatry
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
following order; GH ... #SideEffects #endocrinology
Narcissistic Personality Disorder: Pathogenesis and Clinical Findings • Arrogant, Haughty Behaviors or Attitude - Often display
- Entitlement, Excess ... PersonalityDisorder #Diagnosis #Psychiatry
Anorexia Nervosa: Complications CARDIAC ABNORMALITIES - Functional: Low BP, Sinus bradycardia, prolonged QT interval - Structural: Reduced
- Lethargy or Excess ... mortality rates of all psychiatric ... signs #symptoms #psychiatry
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