The Calgary Guide to Understanding Disease @TheCalgaryGuide
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menstrualcycle ovariancycle allergy diagnosis hypersensitivityreaction anaphylaxis pituitary signs symptoms feedbackloop growthhormone uterinecycle xlinked 21hydroxylasedeficiency 21ohd agammaglobulinemia c5c9deficiency cascade comparison complement
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... GH excess prior ... GH excess after ... signs #symptoms #endocrinology ... #pathophysiology
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... /Symptoms: • GH ... abn lipid • GH ... #FeedbackLoop #endocrinology ... #pathophysiology
X-linked Severe Combined Immunodeficiency (SCID): Pathogenesis and clinical findings #SCID #SevereCombinedImmunodeficiency #XLinked #pathophysiology #immunology
SevereCombinedImmunodeficiency #XLinked #pathophysiology ... #immunology
Type III Hypersensitivity: Pathogenesis and clinical findings Definition: Small antigen-antibody complexes (produced from normal immune response to
HypersensitivityReaction #Allergy #Immunology ... #pathophysiology
Inflammatory Cascade: Pathogenesis and Clinical Findings Continued Innate Immunity • Phagocytosis: (main mechanism) neutrophils and macrophages engulf
#Inflammation #pathophysiology ... #immunology
Anaphylaxis: Pathogenesis Anaphylaxis is a Type 1 hypersensitivity reaction While the primary mechanism of anaphylaxis is mast cell
#Anaphylaxis #pathophysiology ... #immunology
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
following order; GH ... #SideEffects #endocrinology ... mnemonic #GLFTAP #pathophysiology
Anaphylaxis: Signs and Symptoms Anaphylaxis: when any egg of three conditions is met: 1. Acute onset of skin/mucosal
#Anaphylaxis #pathophysiology ... #immunology #diagnosis
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
HypersensitivityReaction #Allergy #Immunology ... #pathophysiology
Primary Hyperthyroidism - Pathogenesis and Clinical Findings Note: Although rare, gestational diseases can lead to thyrotoxicosis due
Hyperthyroidism #endocrinology ... #pathophysiology
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