The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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pathophysiology diagnosis signs criteria growthhormone personalitydisorder pituitary psychiatry antisocial aspd feedbackloop glftap hyperthyroidism macroadenoma masseffects narcissistic npd overproduction primary sideeffects
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
time of onset of GH ... GH excess prior ... GH excess after ... diagnosis #signs #symptoms ... #endocrinology
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... lipolysis Signs/Symptoms ... abn lipid • GH ... excess: - ... #FeedbackLoop #endocrinology
Primary Hyperthyroidism - Pathogenesis and Clinical Findings Note: Although rare, gestational diseases can lead to thyrotoxicosis due
thyrotoxicosis due to excess ... hyperthyroidism due to excess ... Signs/Symptoms: ... Hyperthyroidism #endocrinology
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
following order; GH ... A good mnemonic ... Signs / Symptoms ... #SideEffects #endocrinology ... #mnemonic #GLFTAP
Antisocial Personality Disorder (ASPD): Pathogenesis and Clinical Findings Work & lnterpersonal: • Home Life Troubles - Conflict
assault ASPD Mnemonic ... : CORRUPT - Conforming ... Criteria #Signs #Symptoms ... #Mnemonic #CORRUPT
Narcissistic Personality Disorder: Pathogenesis and Clinical Findings • Arrogant, Haughty Behaviors or Attitude - Often display
of others NPD Mnemonic ... - Entitlement, Excess ... Criteria #Signs #Symptoms ... #Mnemonic #SPEEECIAL
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