The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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diagnosis criteria pathophysiology personalitydisorder psychiatry growthhormone pituitary antisocial aspd avpd cringes dependent dpd excess feedbackloop glftap macroadenoma masseffects overproduction reliance
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... activates lipolysis Signs ... /Symptoms: • GH ... abn lipid • GH ... #FeedbackLoop #endocrinology
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
time of onset of GH ... GH excess prior ... GH excess after ... Overproduction #diagnosis #signs ... #symptoms #endocrinology
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
following order; GH ... A good mnemonic ... Signs / Symptoms ... #SideEffects #endocrinology ... #mnemonic #GLFTAP
Avoidant Personality Disorder (AVPD): Pathogenesis and Clinical Findings • Restraint - Shows excessive restraint in intimate
Avoidant Personality ... others AVPD Mnemonic ... inferior #AVPD #Avoidant ... Psychiatry #Criteria #Signs ... #Symptoms #Mnemonic
Dependent Personality Disorder (DPD): Pathogenesis and Clinical Findings • Difficulties with Activities - Initiation Of projects
themselves • Avoidance ... themselves DPD Mnemonic ... Psychiatry #Criteria #Signs ... #Symptoms #Mnemonic
Antisocial Personality Disorder (ASPD): Pathogenesis and Clinical Findings Work & lnterpersonal: • Home Life Troubles - Conflict
assault ASPD Mnemonic ... : CORRUPT - Conforming ... Psychiatry #Criteria #Signs ... #Symptoms #Mnemonic ... #CORRUPT
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